Many medical conditions will improve or resolve with just 5-10% total body weight loss! This is detailed in the American Association of Clinical Endocrinology/ American College of Endocrinology Obesity guidelines from 2016.
Pre-diabetes > 10%
Diabetes type 2 > 5-15%
High blood pressure > 5-15%
Fatty liver disease > 5-10%
Obstructive Sleep Apnea > 7-11%
Osteoarthritis > 5-10%
Acid reflux disease > 10%
Polycystic Ovarian Syndrome > 5-15%
Asthma > 7-8%